Reevaluation of the Disk Diffusion Method for Sulfonamide Susceptibility Testing of Neisseria meningitidis

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Reevaluation of the disk diffusion method for sulfonamide susceptibility testing of Neisseria meningitidis.

Lack of correlation between quantitative minimal inhibitory concentration (MIC) determinations and disk diffusion susceptibility tests in our laboratory prompted a study to reevaluate the use of the disk diffusion test for sulfonamide susceptibility testing of Neisseria meningitidis. One hundred and sixty-three recent clinical isolates of N. meningitidis were examined for sulfonamide susceptibi...

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Multilaboratory evaluation of disk diffusion antimicrobial susceptibility testing of Neisseria meningitidis isolates.

In 2005, the Clinical and Laboratory Standards Institute published MIC interpretive criteria for 13 antimicrobial agents used for either therapy or prophylaxis of Neisseria meningitidis infections. The MIC method includes the use of lysed horse blood-supplemented Mueller-Hinton broth with incubation in 5% CO2 for 20 to 24 h. Since some clinical laboratories might prefer the option of disk diffu...

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Abstract       Background and Objective: Due to the continuous increase of multidrug-resistant Acinetobacter baumannii strains around the world, decision making for an effective treatment of infections caused by this organism depends on the results of antimicrobial susceptibility tests. In this study, the validity of disk diffusion and E-test methods was assessed b...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 1976

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.10.6.869